Metformin to lose weight without being diabetic, is it dangerous?

Health Tips


It has become fashionable to use metformin to lose weight without having diabetes for several years in gyms, but how should you take metformin to lose weight ? does it really work ?, and is it safe?

  • Metformin is used to lose weight
  • How does metformin help you lose weight?
  • How to take metformin to lose weight?
  • What is the proper dose of metformin to lose weight?
  • How long do you lose weight with metformin?
  • What is the price of metformin to lose weight?
  • Side effects and dangers of using metformin to lose weight
  • What does metformin do?
  • Testimonials of the use of metformin to lose weight

Here we will see all that from the scientific point of view, with medicine based on evidence.

Is metformin used to lose weight?

Yes, according to a double-blind randomized study of 30 non-diabetic obese patients, who were given the drug for 15 days. The result was a decrease in weight and percentage of body fat higher than placebo.

In another study in 154 non-diabetic obese patients, 2500 mg of metformin was given daily to and 6 kilos more on average compared to placebo.

Medications for diabetics with obesity (such as metformin) cause the flow of food from the stomach into the small intestine to be slower, so the feeling of fullness lasts longer.

The function of metformin is to reduce glucose levels and increase insulin sensitivity. Those who consume it are less likely to develop excessive appetite or frequent cravings and thus achieve rapid weight loss.

How does metformin help you lose weight?

Based on research, this antidiabetic has been effective in weight loss in some obese, but science does not yet specify how capable of it.

One theory suggests that because of its ability to decrease appetite, metformin helps lower caloric intake. Another hypothesis is that it is capable of changing the way the body uses and stores the fat in food.

Despite the results of the studies, this medication is not a solution to lose kilos in a short time. For this there are other ways such as diets, supplements and exercises.

How to take metformin to lose weight?

The drug should be consumed between 20 and 30 minutes before each meal. The doctor will determine how many times per day, but some people ingest 1 tablet of 500 mg metformin once or twice a day. The amount is adjusted according to the needs of each person.

 Metformin also helps lose weight in women with Polycystic Ovarian Syndrome , a condition that increases insulin levels. This does not work with acid blood, for example, when lactic acid increases after exercise.

Playing sports after consuming the drug will block its effects, because physical activity releases lactic acid that nullifies its results.

It will be necessary to eat carbohydrates to raise blood sugar when feeling dizzy and avoid hypoglycemia.

What is the proper dose of metformin to lose weight?

Attention: remember to consult your doctor before taking metformin.

You should take up to 2500 mg a day to be more successful; you can start with 500 mg in the morning and at night for 1 week, and then raise the dose to 1000 mg every 12 hours.

The doctor will define the dose of metformin for each patient. It is likely to suggest starting with a low and progressively increasing the amount in a few weeks. The gradual increase in dosage will favor the body’s adaptation to medicine and reduce the risk of its side effects.

The following characteristics will be assessed by the doctor to define the perfect dose.

  • Age and weight
  • Condition of type 2 diabetes.
  • Other health conditions.

What is the maximum dose of metformin?

The maximum dose of metformin is 3000 mg in 24 hours. In people of the third age the dose should be adjusted depending on how the kidneys are working.

How long do you lose weight with metformin?

It is a frequent question, but it is variable from one individual to another. In some individuals its effects can be seen in just two weeks, others need up to 8 weeks to start the weight reduction. The amount of weight and time is not proportional to the dose.

Although it proved to be helpful in losing weight in certain people, the antidiabetic is not a magic pill for that purpose. For this there are other natural and chemical tools.

People who cannot burn fat with this tablet are not at risk of gaining weight, as it is with other medicines to treat type 2 diabetes. This is an advantage.

What is the price of metformin to lose weight?

A generic presentation of 30 tablets of metformin 850 mg costs around 99 Mexican pesos. In the same way, the generic presentation of 30 tablets of metformin 500 mg costs around 65 Mexican pesos. In the United States 100 tablets of 500 mg of metformin costs around US $ 55.

If you choose an original commercial presentation of 500 mg laboratory (30 tablets) can cost 350 Mexican pesos.

Side effects and dangers of using metformin to lose weight

The most common side effect is dizziness when taking metformin to lose weight; most people have no side effects.

The following are the adverse effects caused by metformin to lose kilos.

Gastrointestinal problems such as dizziness, diarrhea, nausea and vomiting.

  • Low back pain
  • Loss of energy
  • Muscle pain.

The use of the medicine can cause nausea, changes in the stomach and diarrhea.

Taking metformin without being diabetic is not dangerous in most people, but it should not be used if your doctor does not prescribe it.

Could your doctor prescribe metformin to lose weight?

Yes. The doctor may prescribe metformin to control and reduce the risks of prediabetes and type 2 diabetes . Also to know if the pill can favor weight loss.

Many patients with type 2 diabetes are obese, so doctors around the world suggest attacking both problems with a single medication. They may even prescribe it to burn kilos without the person having the medical condition, despite the fact that the Food and Drug Administration of the United States, FDA, has not approved metformin for this last use.

This status means that there is less information about how effective medicines are not approved by the FDA to lose weight.

Does metformin harm the liver?

Metabolism of metformin is initially met in the liver. In sensitive patients it can cause cell damage. However, it is a fairly safe medication, even in cases of fatty liver.

It will be a doctor who determines if a patient needs, should or can consume these tablets, the most used in the world for type 2 diabetes. Its use is restricted for people with difficulty to process glucose.

How long does the effect of metformin on the body last?

The elimination half-life is about 17 hours, and in the last 8 hours the therapeutic action is very low, which is why it is indicated at least every 12 hours. After that time the effects of metformin are minimal.

Metabolic changes can be prolonged over time, especially if there has been significant loss of body fat.

How long does metformin work?

The effects on body weight begin to be noticed after 4 weeks of treatment.

How to know if metformin is working?

You can measure its effects in two ways:

  • Through laboratory tests, which reveal an improvement in metabolic values, glycemia and insulin levels, as well as possible liver and kidney effects.
  • Measurement of total body fat. It is not enough to lose weight and height, it is necessary to know how much body fat is lost.

How long can I take metformin?

Metformin can be taken for a long time, but laboratory tests should be done to evaluate toxic effects that do not generate symptoms in the initial phases

Testimonials of the use of metformin to lose weight

Below testimonials from people who have used metformin to lose weight successfully:

Opinions of metformin to lose weight

A long-term investigation among metformin users yielded the following conclusions:

  • Weight loss from the use of metformin tends to occur gradually over one or two years.
  • The amount of weight lost varies among people. The lost weight will be between 2 and 3 kilos.
  • Taking the medication without accompanying it with healthy habits will not guarantee weight loss.
  • People who follow a healthy diet and exercise while taking metformin tend to lose more weight. This could be possible because the drug increases the calories that can be burned with exercises.
  • The lost weight will recover when you stop using the medicine.
  • Leaving healthy habits will recover the kilos eliminated even taking metformin.

How to supplement the use of metformin to lose weight?

A balanced diet will be necessary to potentiate the effects of the antidiabetic and rule out foods that increase the level of sugar in the blood.

There will be no positive effects of metformin on weight loss, but it is accompanied by a separate diet regimen of refined or processed sugars.

What does metformin do?

It is a drug to treat type 2 diabetes according to the American Diabetes Association , many use it to lose weight without diabetes. It is a type of medicine called biguanides. It has effects on the metabolism, decreasing the resistance of insulin in the tissues, mainly in the fatty tissue and its use is being studied to extend the life you can read more of its functions in our article on the uses of metformin .

It is ideal to use if there is obesity and insulin resistance disorders or metabolic syndrome.

What action does metformin have?

It inhibits gluconeogenesis in the liver (that is, the production of sugar in the liver) and glycogenolysis (that is, obtaining glucose through glycogen). It helps improve insulin sensitivity in the muscle. It slows down the absorption of glucose in the intestines.

Functions of metformin

Its main effect is to reduce the levels of sugars in the liver. When there is not so much glucose in the body, no excess insulin is produced; therefore, the appetite decreases considerably.

Contraindications of metformin to lose weight

The following people cannot use metformin to lose weight:

  • Patients with kidney problems.
  • People with heart problems
  • Patients with any problem that causes acidosis.
  • If you are an athlete that competes and your activity takes up glucose for your type of sport. Metformin lowers the blood glucose that an athlete uses to improve their performance.

What else could cause weight loss while using metformin?

If you are losing weight with the administration of metformin, it may or may not be a direct result of the medication, as this may be associated with other factors. For example, some health conditions decrease appetite, which can lead to weight loss. These conditions include:

  • Chronic Obstructive Pulmonary Disease, COPD.
  • Acquired Immunodeficiency Syndrome, AIDS.
  • Parkinson’s disease

Drug interactions of care

Medications used for chemotherapy treatments can cause weight loss due to their effect on appetite. Some used for the thyroid as levothyroxine, liothyronine and liotrix, increase metabolism also affecting a loss of kilos.

Amphetamine, dextroamphetamine and methylphenidate, drugs used for Attention Deficit Hyperactivity Disorder, ADHD, also stimulate size reduction. Problems of the digestive system are added to cause weight loss. Others more:

  • Irritable bowel syndrome.
  • Infections of the stomach or intestines.
  • Surgeries of the stomach or intestines.

What are the adverse symptoms of metformin?

The most common adverse symptoms that affect 10% of people who take metformin are: dizziness, nausea, vomiting, diarrhea, pain in the abdomen.

Is it dangerous to use metformin to lose weight?

Metformin is a relatively safe drug with common side effects that disappear over time. The weight loss obtained during its consumption should be gradual, minimal and without causing alarm.

Ideally, consult with the doctor about the intake of the drug to identify why you are losing more weight than expected and take action.

Assisting the doctor in this situation must be a norm whether metformin is consumed or not. However, if the patient has lost more than 10 pounds in the last 6 months or in a year without knowing why, it will also be a reason for medical assistance.

Common questions about the dose of metformin

What is metformin 500 mg for?

It is the presentation of metformin easier to dose. It is useful when we want to divide the dose in each meal and take at least 3 times a day.

It is also useful when you are starting treatment that low doses are advised that are progressively increased by testing the tolerance and effects of the medication. In such a way, that if the effects are minimal and tolerance is good, the dose can be increased if necessary

What is the use of metformin 850 mg?

This presentation is useful for dosing once or twice a day and therefore, a relatively high dose can be maintained, avoiding several daily doses.

What is the use of metformin hydrochloride 850 mg?

It is equal to metformin 850 mg; there are no changes in the quantity of the basic product.

Is metformin 850 mg used to lose weight?

The dose of metformin should be adjusted to each person. However, we can comment that the minimum dose to lose weight is 850 mg to 1000 mg daily. It should be noted that the effect is best achieved if proper diet and physical exercise is done.

Metformin: slimming or fattening

It is extremely rare that metformin causes weight gain. Cases have been reported but in combination with other medications.

What other things do I need to talk to my doctor?

The doctor will answer all the concerns you have about weight and health. Some of these that you can write down so you do not forget them can be:

  • Do I really need a medication to help me lose weight?
  • Can you recommend a diet and an exercise program to help me lose weight?
  • What is a reasonable goal of weight loss for me?
  • Should I work with a dietitian to help me with my diet?
  • If I lose weight, could I stop taking some of my medications for diabetes, high cholesterol or high blood pressure?
  • Is it safe for me to take metformin to lose weight?

With all the information reviewed you are ready to start a treatment to control type 2 diabetes with this popular drug, thereby also losing a few extra kilos. Finally, do not forget that you must accompany the use of the medication with a healthy lifestyle and with periodic visits to the doctor.

Now you know what metformin is for weight loss. If you liked this article, share it with your friends on social networks so that they also know what it is, what it is for and how metformin and weight loss are linked.

Is it safe to mix metformin with alcohol?

Below an explanatory video of Dr. Julio César Castañeda on how metformin helps lose weight:

Related Wiki Article: Metformin Benefits & Side Effects

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